About Us

Your trusted resource for Botulax information and professional product access

Welcome to Botulax USA, a dedicated online resource focused on Botulax botulinum toxin products and professional medical aesthetics.

Our goal is to provide information about Botulax formulations, specifications, packaging, product strengths, and professional applications in an understandable, well-organized, and practical manner. We are aware that when assessing injectable esthetic products, qualified medical buyers and healthcare professionals require accurate product information.

Gloved hand holding a Botulax 100 unit vial in a clinic

Our approach

Clinician in gloves drawing botulinum toxin from a vial into a syringe

At Botulax USA, we focus on three priorities:

Clear product information

We organize product specifications in an easy-to-understand format, including available unit strengths, formulation details, manufacturer information, and professional-use considerations.

Professional focus

Botulax is a prescription medical product. Our website content is designed to support healthcare professionals and qualified buyers rather than encourage self-treatment or self-administration.

Responsible information

Medical products should always be used according to official product documentation and applicable regulations. Because approvals and indications can vary by country, we encourage healthcare professionals to verify current local requirements before use.

Our commitment

We aim to make information about Botulax products easier to access while maintaining a professional and transparent approach to medical aesthetics.

Botulax 100 unit carton and vial on a pale blue pedestal

What is Botulax?

Botulax is a botulinum toxin type A product manufactured by Hugel, Inc., South Korea. The Botulax product family includes 50U, 100U, and 200U presentations and has been distributed internationally for aesthetic and therapeutic applications. In South Korea, a 150-unit dosage strength is also available as an option for muscle spasticity and blepharospasm.

Hugel has developed a broad medical aesthetics portfolio that includes botulinum toxin products, dermal fillers, and other injectable aesthetic solutions. The company was established in 2001 and has expanded its presence across international markets.

Botulax quality & stability

Hugel Inc. is known for its high-quality products and state-of-the-art facilities, ensuring the stability and durability of its biopharmaceuticals. Their specialized quality control and quality assurance standards keep Botulax at a stable potency during manufacture and distribution, maximizing its outcomes upon administration.

TypeKFDAIn-house
Botulax 50U40–6245–55
Botulax 100U80–12595–115
Botulax 150U120–188142–172
Botulax 200U160–250195–240
Bar chart of potency in units (LD50): three bars each for Botulax 50U, 100U, 150U and 200U, with dotted reference lines at 55, 115, 166 and 227 units.

Botulax also showed excellent stability after reconstitution when the vial is stored properly, specifically at cold (8⁠–⁠15 °C) or freezing temperatures (2⁠–⁠8 °C). Clinical studies highly recommend that Botulax be used within 24 hours of reconstitution following directions for use of the medicine. The graph below displays how Botulax maintains its stability after being diluted depending on the volume unit.

Two line charts: potency in units (LD50) of Botulax 50U, 100U, 150U and 200U over time after reconstitution, in cold storage (0 hours to 4 months) and freezer storage (0 hours to 4 months). Potency declines gradually in both.

Botulax purity

Botulax was developed with 99% purity, containing a high concentration of purified Clostridium botulinum toxin type A. The graph shows that the toxin complex of Botulinum Toxin Type A exists in the 19S (900 kDa), 16S (500 kDa), and 12S (300 kDa) forms, depending on the molecular weight. Each Botulax concentration is a guaranteed highly purified Botulinum toxin strain, ensuring full wrinkle improvement effects.

Sedimentation coefficient of the BoNT/A complex by analytical ultracentrifugation: six samples peak at 19S; diagrams of the 12S, 16S and 19S toxin complex forms. Caption: the toxin complex of Botulinum Toxin Type A exists in the 19S (900 kDa), 16S (500 kDa), and 12S (300 kDa) forms depending on the molecular weight (Putnam, Lamanna and Sharp, 1948; Wagman and Bateman, 1951).

Moreover, Hugel used the technique called SE-HPLC, or Size Exclusion High-Performance Liquid Chromatography, to analyze the Botulax undiluted toxin complex solution for its purity. It resulted in a purity of over 99%, satisfying the parameters of a high-quality neuromuscular solution during clinical trials.

Purity by size exclusion high performance liquid chromatography (SE-HPLC): area percent report showing the main peak at 99.5069% of total area.

Botulax safety & efficacy

Botulax has undergone numerous clinical trials, proving its efficacy and safety upon injection. Studies compared it with other prominent botulinum toxin brands, such as Allergan’s Botox, and Botulax has demonstrated comparable effectiveness. The following studies demonstrate Botulax’s excellent effects on various signs of aging.

Discover our products!

Botulax 50U carton and vial

Botulax 50U

A lower-unit presentation intended for professional use where the applicable product labeling calls for this strength, such as finer facial wrinkles and other superficial conditions.

Botulax 100U carton and vial

Botulax 100U

A commonly supplied presentation containing 100 units of botulinum toxin type A per vial.

Botulax 150U carton and vial

Botulax 150U

A convenient large-dose Botulax formulation for muscle spasticity and facial wrinkle improvement.

Botulax 200U carton and vial

Botulax 200U

A higher-unit presentation intended for professional medical applications, as directed by the applicable labeling, especially in severe cases.

Botulax 300U carton and vial

Botulax 300U

A high-volume formulation for high-dose treatments and larger surface areas, making it convenient and economical for both the clinic and patient.

For questions about product availability, specifications, documentation, or professional purchasing, please contact our team.

Botulax USA — Professional Information for Botulax Products

Frequently asked questions

What makes Botulax a Korean botulinum toxin?

Botulax was developed and manufactured by Hugel in South Korea. Hugel identifies Botulax as a botulinum toxin type A product and reports that its efficacy and safety have been evaluated through clinical trials and years of clinical use.

What Botulax products can I find on Botulax USA?

Our product range may include different Botulax presentations, such as 50U, 100U, 150U, 200U, and 300U, depending on current product availability and applicable market requirements.

Product pages provide information about the individual strength, formulation, packaging, manufacturer, and professional-use considerations.

Are Botulax products considered safe and effective?

Yes, there are several clinical trials and research proving Botulax efficacy and safety for numerous conditions, such as blepharospasm or involuntary eye twitching, glabellar lines, crow’s feet, muscle spasticity, and even cerebral palsy.

Are Botulax units interchangeable with other botulinum toxin brands?

No. Botulinum toxin products can use product-specific potency units, and units should not be assumed to be directly interchangeable between brands. Healthcare professionals should follow the dosing and administration information specific to the product being used.

Can patients purchase and administer Botulax themselves?

Botulax is a prescription medical product intended for professional use. It should be prepared and administered by an appropriately qualified healthcare professional. Botulax USA does not recommend self-administration.

How can I contact Botulax USA?

For questions about product availability, specifications, documentation, or professional purchasing, please contact our team through the information provided on our Contact Us page.

Talk to the Botulax USA team